In the context of vaccines manufactured to prevent COVID-19 pandemic, consider the following statements: 1. The Serum Institute of India produced COVID-19 vaccine named Covishield using mRNA platform. 2. Sputnik V vaccine is manufactured using vector-based platform. 3. COVAXIN is an inactivated pathogen-based vaccine. Which of the statements given above are correct?
Explanation
Statement 1 is incorrect: Covishield, produced by the Serum Institute of India, is a viral vector vaccine. It uses a weakened chimpanzee adenovirus vector to carry genetic material from the SARS-CoV-2 virus into human cells.
Statement 2 is correct: Sputnik V is a vector-based vaccine, similar to Covishield. It uses two different human adenovirus vectors to deliver genetic material coding for SARS-CoV-2 spike proteins.
Statement 3 is correct: COVAXIN, developed by Bharat Biotech, is an inactivated virus vaccine. This means the SARS-CoV-2 virus used in the vaccine is inactivated (killed) so it cannot cause infection, but it still triggers an immune response.